Night-Shift workers test gut bug and herb combo to beat diabetes risk
NCT ID NCT07440147
First seen Feb 28, 2026 · Last updated Jun 22, 2026 · Updated 19 times
Summary
This study tests whether taking a combination of Akkermansia muciniphila (a beneficial gut bacterium) and berberine (a plant compound) can improve insulin sensitivity in night-shift workers. 200 participants from healthcare and industry in Austria and Denmark will receive either the supplements or a placebo for 12 weeks, then switch after a break. The main goal is to see if this approach lowers insulin resistance, a key risk factor for type 2 diabetes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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FH JOANNEUM University of Applied Sciences
RECRUITINGGraz, Styria, 8020, Austria
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Akkermansia muciniphila (a gut bacterium) and berberine (a plant compound) taken as dietary supplements
What this could lead to
If it works, this could point toward a simple supplement combination to help night-shift workers improve insulin sensitivity and reduce their risk of type 2 diabetes.
What could go wrong
This is an early-stage trial with no phase designation, and the supplements may not improve insulin sensitivity more than placebo. Results may not apply to non-shift workers or other populations.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.