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AI takes the Dentist's chair: computer designs tooth replacements in minutes

NCT ID NCT05056948

Knowledge-focused Sponsor: The University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether artificial intelligence (AI) can automatically design a single-tooth dental crown by learning from a patient's other teeth. Researchers removed a virtual tooth from 3D scans of 250 people and let the AI predict the missing tooth's shape and position. The goal was to see if AI could save time and create a better-fitting prosthesis compared to manual design.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
artificial intelligence (AI) computer-assisted design (CAD) software
What this could lead to
If successful, this AI system could speed up the design of dental crowns and reduce the time patients spend in the dentist's chair.
What could go wrong
This is a small, completed study focused on design accuracy, not on long-term fit or patient outcomes. The AI may not work for all tooth shapes or dental conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

250 people

The number who actually took part.

Started

Sep 2021

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

* Patients attended/attending Prince Philip Dental Hospital * Dental undergraduate students from the Faculty of Dentistry, The University of Hong Kong

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subjects with sufficient dentition present for the determination of the upper occlusal plane * Subjects with more than 12 occluding pairs and stable intercuspal position * Subjects with teeth restorations that did not grossly alter its morphology * Subjects who did not undergo orthodontic treatment and/or did not have teeth that rotated more than 45 degrees and/or displaced more than 1.5 mm * Subjects who are of Cantonese descent. Exclusion Criteria: * Subjects with periodontal disease whereby there is pathological tooth migration and alteration of occlusal plane. * Subjects who are under the age of 18 and unable to give consent. * Subjects with extensive teeth restorations that affect the morphology.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental prosthesis

Contacts and locations

Locations

  • Prince Philip Dental Hospital

    Sai Ying Pun, Hong Kong

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