AI-Powered question lists could help blood cancer patients get more from doctor visits
NCT ID NCT07226934
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether an AI-generated personalized question prompt list (GPT-QPL) can help people with lymphoma or multiple myeloma ask more useful questions during their outpatient appointments. Researchers will create tailored question lists for 40 patients using ChatGPT, then measure changes in how confident patients feel communicating with their doctors and how satisfied they are with the information they receive. The goal is to see if this simple AI tool is feasible and helpful for improving patient-doctor communication.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- GPT-QPL (AI-generated personalized question prompt list)
- What this could lead to
- If it works, this could give patients a simple tool to get more useful information from their doctors and feel more in control of their care.
- What could go wrong
- This is a very small, early feasibility study with only 40 participants, so results may not apply to everyone. The AI tool may not be helpful or easy to use for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Eligibility Criteria as determined by Electronic Health Record (EHR) Screening: * Documented diagnosis of lymphoma, as defined by ICD-10 codes C81-C88 or multiple myeloma, as defined by ICD codes C90.0-C90.02 * Has a scheduled follow-up appointment at a participating outpatient oncology clinic within the next month. Participating clinics include: * Dr. David Russler-Germain: Outpatient Lymphoma Clinic * Dr. Michael Slade: Outpatient Multiple Myeloma Clinic * Dr. Dilan Patel: Outpatient Lymphoma Clinic * Undergoing infusion or injection-based systemic therapy intended to cure or manage the disease, as opposed to regimens delivered solely for palliative purposes, at a frequency of once every 1-4 weeks. * For eligible patients with lymphoma, this includes, but is not limited to, commonly prescribed treatment combinations such as R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin/Hydroxydaunorubicin, Vincristine, and Prednisone) for Non-Hodgkin Lymphoma, or ABVD (Adriamycin/Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine) for Hodgkin Lymphoma-both regimens that are frequently administered every three weeks * For patients with multiple myeloma, eligibility will include patients in the "induction" phase of chemotherapy treatment, which frequently requires patients to come in for outpatient appointments once every four weeks as well as patients in a maintenance phase of treatment that otherwise requires them to attend outpatient appointments at a frequency of every one to four weeks * Between the ages of 18-99 at enrollment (Patients older than 99 will be excluded so that the study team is able to elicit questions from WashU ChatGPT using a standardized prompt that describes the patient's age only as specifically as a 10-year decade range (i.e., "I am a patient in my 20's, 30's, 40's, etc. Patients who are 18 or 19 years old will be described in the following manner: "I am a young adult patient in my late teens"). * Able to consent to medical care independently (does not have a legally authorized representative or documented diagnosis of cognitive impairment) Eligibility Criteria as determined by subsequent recruitment phone call or In-person approach after a clinic appointment: * Does not have visual impairments or English literacy limitations that would interfere with ability to engage in an intervention that requires being able to read material on an electronic device and on paper and communicate aloud during appointments with health care providers, based on patient self-report * Able to use email (consent form will be distributed electronically through DocuSign and associated emails), based on successful completion of electronic informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Cheap blood count ratios eyed as window into Myeloma's inflammatory grip
- Can a t-cell engager rescue myeloma that outsmarted CAR-T?
- Can myeloma treatment work without steroids?
- Double-Drug attack on Hard-to-Treat lymphomas
- Banking blood and bone marrow to decode plasma cell disorders
- Chemotherapy plus immunotherapy tested against rare EBV-Driven immune storm