AI could help ER doctors spot heart attacks faster
NCT ID NCT07235657
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether an artificial intelligence (AI) tool can help emergency room doctors interpret heart CT scans more accurately. About 530 adults with chest pain and intermediate risk of a heart attack will be randomly assigned to have their scans read with or without AI assistance. The goal is to see if the AI tool improves the doctors' ability to correctly rule out serious coronary artery disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AI-based coronary CT interpretation software (Angiomics)
- What this could lead to
- If successful, this AI tool could help emergency doctors diagnose heart attacks more accurately and quickly, especially when radiologists are not available.
- What could go wrong
- This is a relatively early-stage trial testing a tool in a controlled setting. The AI may not improve accuracy in real-world practice, and results may not apply to all hospitals or patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 530 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older * Patients presenting to the emergency department with chest pain * Patients assessed as intermediate risk (Heart Score 4-6) Exclusion Criteria: * Prior history of coronary revascularization (coronary artery bypass graft surgery or stent placement) * Presence of intracardiac metallic devices such as pacemaker or prosthetic heart valves * Contraindications to contrast media (e.g., contrast allergy, severe renal impairment with eGFR \< 30 mL/min/1.73 m²) * Patients unable to cooperate (e.g., severe anxiety, non-cooperation)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Yonsei University College of Medicine, Yonsei University Severance Hospital
Seoul, South Korea
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