AI takes the wheel on pain control in the operating room
NCT ID NCT07253012
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests an artificial intelligence system called SEASCAPE that helps doctors manage pain during surgery. The AI monitors patient data in real time and suggests the best dose of a painkiller (remifentanil) to avoid giving too much or too little. 150 adults having planned surgeries lasting 2-4 hours will take part. The goal is to see if the AI can improve pain control and reduce complications compared to standard methods.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Remifentanil (opioid) delivered via target-controlled infusion, guided by an AI copilot system (SEASCAPE)
- What this could lead to
- If successful, this AI system could help doctors give the right amount of pain medicine during surgery, reducing side effects and improving recovery.
- What could go wrong
- This is an early-stage study with 150 participants, so results may not apply to all patients. The AI may not always outperform standard methods, and technical issues could arise.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients scheduled for elective surgery with general anesthesia and anesthesiologist.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients scheduled for elective surgery with general anesthesia. * Surgeries scheduled to last at least two hours. Exclusion Criteria: * Patients undergoing emergency surgery. * Pregnant women. * Presence of a mental or intellectual disability before the hospitalization. * Drug dependence. * Surgeries scheduled for more than 4 hours. * Intraoperative complications requiring changes in routine behavior.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Division de Anestesiologia
NOT_YET_RECRUITINGSantiago, Chile
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Hospital Clinico UC Christus
RECRUITINGSantiago, Chile
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