Mushroom power: could AHCC keep your toddler Cold-Free?
NCT ID NCT07479394
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study tests whether a daily supplement called AHCC, made from shiitake mushrooms, can reduce the number of respiratory infections (like colds) in children aged 2 to 4. Sixty children in daycare will receive either AHCC or a placebo for three months. Researchers will track fevers and measure immune markers to see if the supplement boosts immunity.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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4 to 6 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Children aged 4-6 years old at the time of enrolment 2. Good nutritional status with weight-for-height \> -2, and height-for-age z-score \> -2 based on WHO growth standards 3. Infants in a group setting (daycare centers). 4. No congenital disorder 5. Not suffering from severe coughing or diarrhoea at the time of recruitment 6. Written informed consent will be obtained from parents or legal guardians before enrollment. Exclusion Criteria: * Presence of chronic illnesses or conditions (congenital disorder, genetic syndromes, congenital heart disease, chronic renal failure, cystic fibrosis, etc) * Children who have participated in another clinical intervention study within the past 30 days. * Children who are likely to be transferred to another facility that is not part of the study before completing the follow-up period
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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