Could a Mitochondria-Boosting supplement beat multivitamins for preventing colds?
NCT ID NCT07622147
First seen Jun 25, 2026 · Last updated Jun 30, 2026 · Updated 3 times
Summary
This study tests whether a special combination of supplements (sodium nucleinate, magnesium, vitamin B6, and high-dose vitamin D) can prevent respiratory infections like colds and flu better than standard multivitamins. Two hundred healthy male military recruits in Kazakhstan will take either the new supplement or a standard multivitamin daily for 30 days, and researchers will track infections and immune cell function over 6 months. The goal is to see if boosting the power source inside immune cells (mitochondria) can help prevent infections during the stressful adaptation period of military training.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- sodium nucleinate, magnesium, vitamin B6, and vitamin D3 5000 IU
- What this could lead to
- If it works, this could lead to a better prevention strategy for respiratory infections in high-risk groups like military recruits.
- What could go wrong
- This is a small, early-stage trial with only 200 participants, so results may not apply to the general population. The intervention is a dietary supplement, so any effect is likely modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2027
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 27 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male military recruits aged 18-27 years * Starting initial military training at the Military Clinical Hospital of the Ministry of Defense of the Republic of Kazakhstan (Almaty) * Signed informed consent * No acute infectious diseases at enrollment * Willingness to comply with the study protocol for 6 months * Absence of any exclusion criteria Exclusion Criteria: * Chronic immunodeficiency states (HIV infection, congenital immunodeficiencies, current immunosuppressive therapy) * Severe chronic diseases in decompensation stage (diabetes mellitus, renal failure, hepatic failure, heart failure) * Allergy or hypersensitivity to any components of the study interventions (multivitamin, sodium nucleinate, magnesium, vitamin B6, vitamin D) * Use of vitamin-mineral complexes or immunomodulators within the last 3 months prior to enrollment * Hypercalcemia (serum calcium \>2.6 mmol/L) or history of urolithiasis * Hypermagnesemia (serum magnesium \>1.1 mmol/L) * Sarcoidosis or other granulomatous diseases * Refusal or inability to provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
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