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New study tests AGZ for better sleep and relaxation

NCT ID NCT07311434

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a daily supplement called AGZ can help adults aged 25-59 who have trouble sleeping feel more relaxed in the evening, sleep better, and have more energy in the morning. About 300 people will take AGZ or a placebo for 30 days and answer questionnaires about their sleep and stress. The goal is to see if AGZ improves sleep quality and relaxation without using prescription sleep aids.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

22 to 59 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female. * Age 25-59 years. * BMI ≥18.5 and ≤29.9 kg/m². * Currently experiencing issues with sleep quality, falling asleep, staying asleep, or waking during the night. * RU-SATED score ≤17. * Willing and able to follow the study protocol. * Willing to discontinue any other supplements (including nootropics, adaptogens, calming herbs), medications, herbal remedies, or over-the-counter sleep medications (e.g., zolpidem, diphenhydramine, Benadryl, ZzzQuil, Unisom, magnesium or melatonin products) used to assist with sleep during the study. * Agree to limit alcohol intake within approximately 4 hours of bedtime throughout participation. * Agree to limit caffeine intake to ≤400 mg/day (about 3-4 cups of coffee) and avoid ingestion of caffeine-containing products after 2:00 PM during the study period. * Generally healthy and not living with any uncontrolled chronic disease. * Resides in the United States. * Willing to discontinue any restricted products and adhere to all required study assessments. Exclusion Criteria: * Diagnosed chronic sleep conditions (e.g., insomnia, narcolepsy, REM Behavior Disorder, moderate to severe restless leg syndrome, sleep apnea). * Current use of sleep-tracking technology (e.g., wrist-worn trackers, rings, smartphone apps) that could influence sleep behavior or perception. Women currently undergoing perimenopause or experiencing vasomotor symptoms (e.g., night sweats). * Use of hormone therapy (estrogen, progesterone, phytoestrogens) within the last 3 months. * Diagnosed psychiatric disorders including major depressive disorder with acute symptoms, bipolar disorder, generalized anxiety disorder with active symptoms, and PTSD with frequent nightmares. * Diagnosed neurodegenerative or chronic pain disorders, including Parkinson's disease, Alzheimer's disease, or uncontrolled fibromyalgia. * Regular prescribed stimulant use (e.g., amphetamines such as Adderall/Vyvanse; methylphenidate such as Ritalin/Concerta; modafinil/armodafinil). * Current use of CNS-activating antidepressants (bupropion, fluoxetine, venlafaxine, sertraline). * Current or recent use of cannabis or THC-containing products (recreational or medicinal marijuana, CBD with measurable THC, synthetic cannabinoids) within the past 30 days. * Employment in jobs disrupting nighttime sleep (e.g., night shift, rotating shift, excessive travel). * Current use of prescription sleep aids. * Introduction of any new sleep-related supplements, medications, herbal remedies, or melatonin products during the study. * Use of any prescription or OTC products with sedative properties (e.g., melatonin, diphenhydramine, doxylamine, valerian, ZzzQuil, Advil PM) within 4 weeks prior to enrollment or habitual use ≥3 times per week prior to enrollment unless investigator-approved. * Allergy or sensitivity to any study product ingredients. * Pregnant, breastfeeding, or trying to conceive during the study period. * History of substance abuse. * Heavy alcohol use (≥8 drinks/week for women or ≥15 drinks/week for men). * Participation in another research study now or within the next 7 weeks. * Any condition or behavior that, in the investigator's judgment, may interfere with study participation or data integrity.

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Conditions

The condition(s) this trial relates to.

Disorders of Excessive Somnolence sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Alethios (Virtual Study Platform)

    RECRUITING

    San Francisco, California, 94117, United States

    Contact Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.