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Could grilled nuggets stress your kidneys? tiny study investigates

NCT ID NCT02695251

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed study looked at whether advanced glycation end products (AGEs) – compounds formed when food is cooked at high heat – affect kidney blood flow and oxygen levels. Ten healthy young men ate either a low-AGE meal (eggs) or a high-AGE meal (mixed nuggets), and their kidneys were scanned with special MRI and PET imaging. The goal was to see if AGEs alone, rather than protein in general, trigger changes in kidney function that might be linked to chronic kidney disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low AGE meal (eggs) and high AGE meal (mixed nuggets)
What this could lead to
If it works, this could clarify whether AGEs in food are a key driver of kidney function changes, potentially guiding dietary advice for kidney health.
What could go wrong
This is a very small, early study in only 10 healthy young men, so results may not apply to older adults or people with kidney disease. It measures short-term effects only.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

10 people

The number who actually took part.

Start date

Feb 2016

Finished

Jul 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy males subjects * age between 18 and 30 years old Exclusion Criteria: * Kidney disease * Diabetes * Obesity * Hypertension * Non Steroidal Anti Inflammatory Drug treatment (NSAIDS) * MRI Contra indications * Myeloma * High basal Radiation exposure : more than 1 milliSievert (mSv) in the last 6 months

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kidney function tests

Contacts and locations

Locations

  • Service de Néphrologie - Hôpital Edouard Herriot

    Lyon, 69437, France

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