Could grilled nuggets stress your kidneys? tiny study investigates

NCT ID NCT02695251

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed study looked at whether advanced glycation end products (AGEs) – compounds formed when food is cooked at high heat – affect kidney blood flow and oxygen levels. Ten healthy young men ate either a low-AGE meal (eggs) or a high-AGE meal (mixed nuggets), and their kidneys were scanned with special MRI and PET imaging. The goal was to see if AGEs alone, rather than protein in general, trigger changes in kidney function that might be linked to chronic kidney disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low AGE meal (eggs) and high AGE meal (mixed nuggets)

What this could lead to

If it works, this could clarify whether AGEs in food are a key driver of kidney function changes, potentially guiding dietary advice for kidney health.

What could go wrong

This is a very small, early study in only 10 healthy young men, so results may not apply to older adults or people with kidney disease. It measures short-term effects only.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service de Néphrologie - Hôpital Edouard Herriot

    Lyon, 69437, France