Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Exercise boosts brain blood flow in aging veterans, study finds

NCT ID NCT03803904

Knowledge-focused Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a 12-week indoor cycling program could improve brain blood flow and function in 37 older veterans (ages 65-80) who did not exercise regularly. Researchers measured brain health before and after the exercise program using MRI scans. The goal was to learn how exercise affects brain aging and may help prevent diseases like dementia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

37 people

The number who actually took part.

Started

Apr 2019

Finished

Jan 2026

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 65-80 who do not regularly exercise * defined as exercising less than 20 minutes twice per week * Are willing and able to cooperate with assessments and interventions * Participant will be quantified at or below the "poor" range for cardiovascular fitness as assessed by a volume of oxygen (VO2) test * 26.0 ml/kg/min for males * 21.0 ml/kg/min for females) * 26 on the MoCA to meet the criteria for cognitively intact * Participants will be free from diseases affecting cognition or that would interfere with their ability to engage in aerobic exercise - including but not limited to: * chronic heart * liver * kidney disease * Free from diseases/injuries directly affecting brain functions - including but not limited to: * significant closed head injury * open intracranial wounds * stroke * epilepsy * degenerative diseases of the nervous system * All subjects will speak English as a primary language and will have at minimum a high school diploma so that behavioral/cognitive measures reflect effects of aging and aerobic exercise and not unfamiliarity with the English language or a lack of education Exclusion Criteria: * Potential participants with major psychiatric disorder - including but not limited to: * psychosis * major depression * bipolar disorder * Individuals with ongoing drug or alcohol abuse and severe hypertension (systolic BP \> 200 or diastolic BP \> 110 mm Hg or subjects taking three or more antihypertensive medications * Participants must not have conditions incompatible with MRI - including but not limited to: * ferrous metal implants * cardiac pacemakers or similar devices * claustrophobia * morbid obesity * Persons engaging in significant skilled manual movements regularly will be excluded so that behavioral/motor measures reflect the effects of age and aerobic exercise and not the effects of frequent practice

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Aging are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging

Contacts and locations

Locations

  • Atlanta VA Medical and Rehab Center, Decatur, GA

    Decatur, Georgia, 30033-4004, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.