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New combo targets Hard-to-Treat lung cancers after first therapy fails

NCT ID NCT05616624

First seen Nov 20, 2025 · Last updated May 24, 2026 · Updated 23 times

Summary

This study tests a new three-drug combination (ADI-PEG 20, gemcitabine, and docetaxel) in people with small cell or non-small cell lung cancer whose disease has worsened after initial treatment. The first part of the study finds the safest dose, and the second part checks how well the combination shrinks tumors or keeps them stable. About 31 participants are expected to enroll.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Inova Schar Cancer Institute

    Fairfax, Virginia, 22031, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.