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Can computer brain training boost ADHD treatment in people with addiction?

NCT ID NCT06906328

Disease control Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a 16-week cognitive remediation program (brain training using PRESCO® software) to standard ADHD medication (methylphenidate) improves daily functioning in adults with ADHD and at least one addiction. 248 participants will be split into two groups: one gets the brain training plus medication, the other gets medication alone. The main goal is to see if more people in the brain training group achieve a 30% improvement in their functional impairment score by the end of treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
methylphenidate (ADHD medication) plus a cognitive remediation program using PRESCO® software
What this could lead to
If it works, this could point toward a more effective treatment approach for adults with both ADHD and addiction, improving their daily functioning.
What could go wrong
This is an early-stage study without a formal phase, so results may not be conclusive. The cognitive program is time-intensive (16 weeks), and benefits may not last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 248 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age over 18; * Diagnosis of ADHD confirmed by DIVA-5 interview following a specialized ADHD-addiction(s) consultation; * Indication for MPH treatment according to European recommendations (J. J. S. Kooij et al., 2019) and absence of contraindications (particularly cardiological); * Presence of at least one comorbid addictive disorder (SUD and/or BA); * Having given their consent to take part in the study; * Being affiliated to the French social security system or benefiting from such a system. Exclusion Criteria: * Presence of disorders of the higher functions or difficulties in reading or writing the French language making it impossible to collect data; * Pregnant or breast-feeding woman; * Person deprived of liberty; * Person under compulsory psychiatric care; * Participation in another interventional research protocol involving another psychotherapeutic or pharmacological intervention that may have an impact on clinical outcome; * Guardianship or safeguard of justice. * Patients who consumned psychoactive substances within 12 hours prior to their visit.

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Conditions

The condition(s) this trial relates to.

attention deficit-hyperactivity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADHD-add

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    6 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CH Georges Daumézon - Bouguenais

    NOT_YET_RECRUITING

    Bouguenais, Loire-Atlantique, 44342, France

  • CHRU Brest

    NOT_YET_RECRUITING

    Brest, Brittany Region, 29609, France

  • CHRU de Tours

    NOT_YET_RECRUITING

    Tours, Centre-Val de Loire, 37000, France

  • CHU Nantes

    RECRUITING

    Nantes, France

  • EPSM Georges Daumézon (Fleury-les-Aubrais, Loiret)

    NOT_YET_RECRUITING

    Fleury-les-Aubrais, Centre-Val de Loire, 45400, France

  • EPSM du Finistère Sud

    NOT_YET_RECRUITING

    Quimper, Brittany Region, 29000, France