Can online therapy shield aging brains after the ICU?
NCT ID NCT06627894
First seen Jan 11, 2026 · Last updated Jun 19, 2026 · Updated 27 times
Summary
This study tests whether an internet-based cognitive behavioral therapy program, called Good Days Ahead, can reduce depression and slow down memory and thinking problems in older adults who have been in the intensive care unit (ICU). The trial will enroll 300 people aged 50 and older who have depressive symptoms after an ICU stay. Participants will either receive the online therapy or standard depression education and monitoring, and researchers will track changes in their thinking abilities and quality of life over time.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Eskenazi Hospital
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IU Health Methodist Hospital
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Internet-based cognitive behavioral therapy (Good Days Ahead)
What this could lead to
If successful, this could provide a practical, home-based treatment to improve mood and potentially slow memory and thinking problems in older adults after a serious illness.
What could go wrong
This is a relatively early-stage trial (Phase NA) testing a behavioral intervention, not a drug. The effect on cognitive decline is uncertain, and benefits may be modest or not apply to everyone.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.