New catheter aims to clear stroke clots faster
NCT ID NCT07367100
First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 4 times
Summary
This study tests a new device called the Adaptive Tip Catheter for removing blood clots in people having a severe stroke. About 74 adults will receive the catheter procedure within 24 hours of stroke symptoms. The goal is to see if the device can restore blood flow in the brain with fewer attempts and without needing extra treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Adaptive Tip Catheter (a medical device used to remove blood clots from brain arteries)
- What this could lead to
- If it works, this catheter could help doctors remove stroke-causing clots more quickly and completely, potentially reducing brain damage and improving recovery.
- What could go wrong
- This is a small, early study with only 74 participants. The device may not work better than existing methods, and there are risks like vessel damage or bleeding during the procedure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 74 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Age greater than or equal to (\>=) 18 years, less than or equal to (\<=) 90 years, at the time of consent * Signs and symptoms consistent with the diagnosis of acute ischemic stroke in the anterior circulation that can be treated with endovascular thrombectomy approaches * Endovascular treatment can be initiated (defined as access puncture) within 24 hours from time last known well * Baseline National Institutes of Health Stroke Scale (NIHSS) score \>= 6 * Baseline Alberta Stroke Program Early CT Score (ASPECTS) \>= 3 * A signed and dated Informed Consent Form (ICF) or Investigator Statement for emergency procedure (as allowed according to country regulations and approved by EC) has been obtained Exclusion criteria: * Known pregnancy, as evidenced by positive pregnancy test for women of childbearing potential or breast feeding * Life expectancy less than (\<) 90 days prior to stroke onset * Known hemorrhagic diathesis disorder, coagulation factor deficiency or oral anticoagulant therapy with known International Normalized Ratio (INR) greater than (\>) 3.0 * Clinical symptoms and/or CT/MRI evidence suggestive of bilateral stroke or stroke in multiple vascular territories, defined as occlusions in more than one vessel not downstream from each other (for example, bilateral anterior circulation, anterior/posterior circulation) * Clinical history, past imaging or clinical judgement suggest that the intracranial occlusion is chronic * Computed Tomography/ Magnetic Resonance Imaging (CT/MRI) evidence of recent/fresh hemorrhage * Baseline CT or MRI showing mass effect * Currently participating in an investigational (drug, device, etc.) clinical trial that may confound study endpoints. Patients in observational, natural history, and/or epidemiological studies not involving intervention are eligible * Cerebral catheter angiographic evidence of pre-existing arterial disease, that potentially impacts treatment and/or outcome (for example, vasculitis) * Any occlusion or stenosis that limits device access to the target area (for example, carotid dissection, tandem occlusions) or requiring acute stenting to achieve access * Cerebral catheter angiographic evidence of multiple cerebrovascular occlusions, defined as occlusions in more than one vessel not downstream from each other (for example, bilateral anterior circulation, anterior/posterior circulation) * Excessive vascular access tortuosity that will likely prevent endovascular access with the adaptive tip catheter (ATC) * Baseline expanded thrombolysis in cerebral infarction (eTICI) \> 1
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
10 sites in 3 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHRU de Tours
RECRUITINGTours, 37000, France
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CHU Bordeaux
RECRUITINGBordeaux, 33076, France
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Centre Hospitalier Universitaire de Toulouse - Hopital Purpan
RECRUITINGToulouse, 31059, France
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Ghent University Hospital
RECRUITINGGhent, 9000, Belgium
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Stadtisches Klinikum Solingen gemeinnutzige GmbH
RECRUITINGSolingen, 42653, Germany
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UZ Antwerpen
RECRUITINGEdegem, 2650, Belgium
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Universitaetsklinikum Heidelberg
RECRUITINGHeidelberg, 69120, Germany
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Universitaetsmedizin Mainz
RECRUITINGMainz, 55101, Germany
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Universitair Ziekenhuis Leuven
RECRUITINGLeuven, 3000, Belgium
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Universitatsklinikum Schleswig Holstein Kiel
RECRUITINGKiel, 24105, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a checklist and heart monitor stop repeat strokes?
- Heart hole or stroke trigger? global registry tracks who gets closure and what happens next
- Two ways to catch a hidden heart rhythm after stroke
- Blood test may reveal who recovers after a stroke
- Can a smart bracelet and app stop a second stroke?
- Pharmacist and coach team takes aim at blood pressure after stroke