2,000 heart attack patients enrolled in landmark Data-Gathering study
NCT ID NCT07522164
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is observing 2,000 people who have had a heart attack to collect detailed medical information, images, and blood samples. Researchers will use this data to better understand different types of heart attacks and find new ways to predict and prevent future heart problems. The goal is to improve personalized treatment for heart attack patients.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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2,000 people
The number who actually took part.
- Started
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Apr 2025
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A total of 2,000 adult patients diagnosed with Acute Myocardial Infarction (AMI) will be recruited from four major tertiary medical centers in Shanghai, China. The cohort will include adult patients of all genders, representing a typical Chinese AMI population. Within this overall cohort, a select subgroup of approximately 200 patients, exhibiting specific high-risk clinical phenotypes of AMI (including those with vulnerable plaques, Myocardial Infarction with Non-obstructive Coronary Arteries \[MINOCA\], and borderline coronary lesions), will undergo deeper clinical and molecular phenotyping. This is an observational cohort study.
- Ages
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14 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients diagnosed with Acute Myocardial Infarction (AMI), regardless of age or gender. * Patients willing and able to provide informed consent. Patients identified to be part of specific high-risk AMI subgroups (for deep phenotyping), including: * AMI patients with high-risk vulnerable plaques (e.g., thin-cap fibroatheroma, large lipid core) identified by intracoronary imaging (OCT/NIRS). * AMI patients with non-obstructive coronary arteries (coronary stenosis \<50% on angiography) and diagnosis confirmed by cardiac MRI (MINOCA). * AMI patients with borderline coronary lesions (50%-80% stenosis on angiography or CTA) requiring functional assessment (e.g., FFR/QFR/IVUS). Exclusion Criteria: * Presence of severe non-cardiovascular comorbidities that would limit participation or confound study results. * Inability or unwillingness to comply with long-term follow-up requirements. * Patients who refuse to provide informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Zhongshan Hospital, Fudan University
Shanghai, 200000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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