Can a simple touch or cold pack make shots less painful?
NCT ID NCT07049640
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether acupressure or cold application to acupressure points before a ventrogluteal injection could reduce pain, anxiety, and improve comfort. 102 adults who needed daily penicillin injections took part. Researchers measured pain, anxiety, comfort, and vital signs after each technique.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- acupressure and cold application
- What this could lead to
- If effective, these simple techniques could offer drug-free ways to ease pain and anxiety during injections.
- What could go wrong
- This is a small, completed study without a placebo control, so results may not be widely applicable. The effects could be due to natural recovery or attention from staff.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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102 people
The number who actually took part.
- Started
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Jul 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18-65 years old, * Patients prescribed at least two doses of penicillin per day, * There is an indication for injection administration * Volunteer to participate in the research will be included. Exclusion Criteria: * Volunteer to participate in the research will not be included.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Siirt Training and Research Hospital
Siirt, Siirt, 47200, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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