Could a digital stethoscope detect heart disease before It's too late?
NCT ID NCT07496775
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new digital stethoscope that listens for subtle changes in heart sounds to detect coronary artery disease and valve problems earlier. Researchers will record heart sounds from 500 adults who are already scheduled for heart scans or echocardiograms. The goal is to see if this simple, non-invasive device could one day be used in GP surgeries to spot heart disease sooner.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- digital stethoscope device
- What this could lead to
- If successful, this could lead to a simple, non-invasive way to detect heart disease earlier in GP surgeries, potentially speeding up treatment.
- What could go wrong
- This is an early-stage study that only collects sounds from people already scheduled for scans. It does not yet test if the device works in real-world settings or improves outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients referred to Department of Cardiology, Cambridge University NHS Foundation Trust.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants aged ≥18 years * Able to provide written, informed consent * Has undergone angiography in the previous 6 months and scheduled to undergo transthoracic echocardiography, or has undergone transthoracic echocardiography in the previous 6 months and scheduled to undergo angiography, or is scheduled to undergo transthoracic echocardiography and angiography within 6 months. * Angiography and echocardiography performed within Cambridge University Hospitals NHS Foundation Trust. Exclusion Criteria: * Haemodynamic instability * STEMI or high risk NSTEMI * Anginal symptoms at rest * Heart failure symptoms with NYHA 4 * Cardiovascular related admission or event occurring between imaging studies * Uncontrolled symptomatic arrhythmia * Acute pulmonary embolism * Acute aortic dissection * Previous valve intervention * Suspected endocarditis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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