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Sharpening the picture: new MRI technique could spot hidden knee injuries

NCT ID NCT05806034

Diagnosis Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new MRI technique called diffusion tractography to better diagnose partial tears of the anterior cruciate ligament (ACL) in the knee. Standard MRI often cannot tell how severe a partial tear is, making treatment decisions difficult. Researchers enrolled 30 adults with knee injuries and used the new scan to measure a score called the anisotropy coefficient, which may indicate the degree of damage. The goal is to improve diagnosis and guide whether a patient needs surgery or physical therapy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tractography MRI sequence protocol
What this could lead to
If successful, this could give doctors a more precise way to diagnose partial ACL tears, helping to choose between physical therapy or surgery.
What could go wrong
This is a small, early study with only 30 people. The new MRI method may not prove more useful than standard scans, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Feb 2023

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years old, * Patient referred for non-enhanced knee MRI for traumatism. * Affiliation to a social security program, Exclusion Criteria: * Person under guardianship or curators, * Any contraindications to MRI

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acl-injury MRI Tractography

Contacts and locations

Locations

  • CHU Amiens Picardie

    Amiens, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.