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Knee surgery showdown: which tendon graft works best?

NCT ID NCT07671729

Disease control Sponsor: Acibadem University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of tendon grafts used to repair a torn anterior cruciate ligament (ACL) in the knee. Sixty people scheduled for ACL surgery will be randomly assigned to receive either a quadriceps tendon graft or a peroneus longus tendon graft. Researchers will measure knee function, return to sports, ankle strength, and walking patterns at 6 and 12 months after surgery to see which graft leads to better outcomes and fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Quadriceps tendon autograft or peroneus longus tendon autograft
What this could lead to
If one graft proves better, it could improve knee function and return-to-sport rates after ACL surgery while reducing donor-site problems.
What could go wrong
This is a small, early-stage trial with only 60 people, so results may not apply to everyone. Both grafts have known risks like pain or weakness at the harvest site.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with anterior cruciate ligament rupture * Patients scheduled for primary anterior cruciate ligament reconstruction * Age between 18 and 50 years * Ability to provide informed consent * Willingness to comply with postoperative rehabilitation and follow-up evaluations Exclusion Criteria: * Previous ligament reconstruction surgery on the affected knee * Multi-ligament knee injuries requiring additional ligament reconstruction * Severe osteoarthritis of the knee * Revision anterior cruciate ligament reconstruction * Neuromuscular disorders affecting lower extremity function * Active infection * Inability to comply with follow-up protocol

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament injury Anterior cruciate ligament rupture

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Acibadem Fulya Hospital, Sport Medicine Center

    RECRUITING

    Istanbul, Besiktas, 34349, Turkey (Türkiye)

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