Knee surgery showdown: which graft gets athletes back in the game faster?
NCT ID NCT07573293
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 65 professional athletes who had ACL reconstruction surgery using either a bone-patellar tendon-bone graft or a hamstring tendon graft. Researchers measured muscle strength, knee function, and how quickly athletes returned to their sport, following them for up to five years. The goal was to see which graft type leads to better recovery and fewer complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- surgical procedure using either bone-patellar tendon-bone or hamstring tendon autograft
- What this could lead to
- If successful, this could help surgeons choose the best graft for professional athletes to improve recovery and return to sport.
- What could go wrong
- This is a small, completed study with only 65 participants, so results may not apply to all athletes. Both graft types have known risks like pain or re-injury.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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65 people
The number who actually took part.
- Started
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Feb 2018
- Finished
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Jun 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Professional athletes actively engaged in competitive sports * Age between 18 and 35 years * Primary isolated anterior cruciate ligament (ACL) rupture confirmed clinically and by MRI * Indicated for arthroscopic ACL reconstruction * Willingness to participate and provide informed consent Exclusion Criteria: * Multiligamentous knee injuries * Previous ACL reconstruction on the affected knee * Lower limb malalignment * Advanced chondral lesions requiring additional surgical procedures * Associated fractures around the knee * Inability to comply with follow-up protocol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kasr Al-Ainy Hospital, Cairo University
Cairo, Cairo Governorate, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can the ankle fully recover after donating a tendon for ACL repair?
- Mind over knee: can psychological readiness predict a safe return to sport after ACL surgery?
- Extra nerve block may ease pain after ACL repair
- Blood flow cuffs or instrument massage: which boosts ACL recovery best?