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Can a common supplement ease arthritis pain and lower blood sugar?

NCT ID NCT07660081

Disease control Sponsor: Khyber Medical University Peshawar Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 18, 2026 · Updated 3 times

Summary

This study tests whether acetyl L-carnitine, a dietary supplement, can help reduce pain, inflammation, and improve blood sugar control in obese, diabetic, postmenopausal women with osteoarthritis. One hundred women will take either the supplement or a placebo for 12 weeks, alongside their usual treatment. Researchers will measure changes in symptoms, blood markers, and joint health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
acetyl L-carnitine (a dietary supplement)
What this could lead to
If it works, this could point toward a simple supplement to help manage osteoarthritis symptoms and improve blood sugar control in this specific group.
What could go wrong
This is a small, early-stage trial with only 100 participants. The supplement may not show meaningful benefits, and results may not apply to other groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Dec 2025

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 65 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 55-65 years 2. Duration of menopause 2-15 years. 3. Duration of diabetes 5-15 years 4. BMI Obese ≥30 kg/m2 5. Grade≥2 K\&L on radiologic examination Exclusion Criteria: * Female patients with osteoarthritis meeting the following criteria will be excluded from the study; 1. Age˂55 ˃65yrs 2. Post-menopausal duration of ˂2yrs 3. Duration of diabetes ˂ 5years 4. Patients with alcohol abuse, asthma, cardiac disease, chronic gastric problems (malabsorption, crohn's disease chronic diarrhea), non-diabetes related renal disease,ovariectomy, rheumatoid arthritis or other rheumatic inflammatory diseases, smoking 5. Patients taking steroids (oral/ injections) 6. Patients with a history of parathyroid and thyroid surgery/dysfunction

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder osteoarthritis type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity Osteoarthritis Type 2 diabetes

Contacts and locations

Locations

  • Khalifa Gulnawaz Teaching Hospital, DHQ Teaching Hospital

    Bannu, KPK, 28100, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.