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A 15-Minute heart MRI could speed up diagnosis of coronary artery disease

NCT ID NCT07729111

Diagnosis Sponsor: University of Leicester Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether an accelerated heart MRI scan, taking only 15 to 20 minutes, can diagnose coronary artery disease as accurately as the standard 45- to 50-minute scan. About 2,000 adults with suspected coronary heart disease will be randomly assigned to receive either the standard or the faster scan. The study will compare clinical outcomes and patient comfort to see if the shorter scan can safely increase access to this non-invasive diagnostic test.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
accelerated stress cardiovascular magnetic resonance (CMR) scan
What this could lead to
If successful, the faster scan could allow more patients to be diagnosed each day, reduce wait times, and improve patient comfort.
What could go wrong
The accelerated scan may not be as accurate as the standard version, potentially leading to missed diagnoses or unnecessary follow-up tests.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 2,022 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

May 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria * patients \>18 years of age referred for routine clinical stress CMR: * A) with chest pain or angina equivalent OR o B) with heart failure/suspected heart failure and referred for diagnosis of suspected CAD or evaluation of heart failure aetiology * Willing and able to consent to participate in the trial Exclusion criteria * standard exclusion criteria for clinical stress CMR i.e.: * absolute contraindications to CMR (non-conditional cardiac implantable electronic devices, metallic implants/foreign bodies), * contraindications to adenosine (severe pulmonary disease, sinus-node/high-grade atrioventricular disease) * severe kidney dysfunction (estimated glomerular filtration rate \[eGFR\] \<30ml/min/1.73m2) * uncontrolled arrhythmia or unstable chest pain * severe claustrophobia * previous invasive coronary angiography (within 12 months) with normal angiographic assessment and referred for CMR diagnosis of CMD

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cad - coronary artery disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.