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1,000 eye photos could teach AI to spot blindness early

NCT ID NCT06924021

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is collecting eye images from 1,000 adults aged 50 and older, with or without age-related macular degeneration (AMD), from up to 25 countries. The goal is to create a high-quality, diverse dataset that researchers can use to train artificial intelligence (AI) to screen for AMD. Participants will provide images of their eyes but will not receive any treatment as part of this study.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Approximately 1000 participants from up to 25 sites in the United States, Europe, Asia, South America, Africa, and Australia will be enrolled and balanced by age, sex, and AMD level (worse eye selected as study eye). Every region listed above may not be represented and additional regions/countries not listed above may be included.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants greater than or equal to 50 years of age at time of signing Informed Consent Form * Willing to comply with all study procedures and sign the Informed Consent Form (ICF) * Individuals with normal healthy eyes or diagnosed with any stage of Age-Related Macular Degeneration (treatment naïve patients with early, intermediate, or late AMD). The diagnosis and eligibility review will be confirmed by Central Reading Center. Exclusion Criteria: * Therapeutic treatment for any type of AMD, in either eye. Supplements, such as AREDS2 formula, are allowed. * Unable to acquire adequate quality images, as evaluated by the Central Reading Center * Severe vision loss requiring urgent surgery * Contraindicated for acquiring retinal images due to narrow anterior chamber angles or hypersensitivity to light * A systemic or ocular condition that in the opinion of the Investigator would preclude participation in the study * Unwilling to sign informed consent form * Currently or previously enrolled in an interventional AMD clinical trial

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    14 sites in 7 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Adelaide Eye and Retina Centre

    NOT_YET_RECRUITING

    Adelaide, 5000, Australia

  • Aga Khan University

    RECRUITING

    Karachi, 74800, Pakistan

  • Aravind Eye Hospital

    RECRUITING

    Chennai, Tamil Nadu, 641014, India

  • Bergstrom Eye Research LLC

    RECRUITING

    Fargo, North Dakota, 58103, United States

  • Centre Hospialier Intercommunal de Paradis (Centre Monticelli Paradis)

    NOT_YET_RECRUITING

    Marseille, 13008, France

  • Charles Research Center

    NOT_YET_RECRUITING

    Buenos Aires, Argentina

  • Erie Retina Research

    RECRUITING

    Erie, Pennsylvania, 16507, United States

  • Retina Consultants of Texas (Houston)

    RECRUITING

    The Woodlands, Texas, 77384, United States

  • Retina Foundation of the Southwest

    RECRUITING

    Dallas, Texas, 75231, United States

  • Sankara Nethralaya, Medical Research Foundation

    RECRUITING

    Chennai, Tamil Nadu, 600006, India

  • University Station Eye Care Clinic

    RECRUITING

    Madison, Wisconsin, 53705, United States

  • University of Bonn - Department of Ophthalmology

    NOT_YET_RECRUITING

    Bonn, 53127, Germany

  • University of Utah - John A. Moran Eye Center

    RECRUITING

    Salt Lake City, Utah, 84132, United States

  • Valley Retina Institute

    RECRUITING

    McAllen, Texas, 78503, United States

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