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Can a simple belly press make liver cancer radiation more precise?

NCT ID NCT07745153

Disease control Sponsor: Southern Medical University, China Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This trial is testing a new abdominal compression technique to reduce breathing-related movement of liver tumors during radiation therapy. The study will compare this novel method with current compression devices and traditional thermoplastic masks in 120 adults receiving radiation for liver cancer. The goal is to see if the new technique can keep tumors as still or stiller, which could make radiation more accurate and effective.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A novel abdominal compression positioning technique used during stereotactic body radiation therapy (SBRT) for liver tumors
What this could lead to
If effective, this technique could improve the precision of radiation therapy for liver cancer, potentially leading to better tumor control and fewer side effects.
What could go wrong
This is a relatively early-stage study, and the new technique may not prove better than existing methods. There are also potential risks from the compression itself, such as discomfort or breathing difficulties.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

120 people

The number who actually took part.

Started

Jan 2025

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who receive radiotherapy at Nanfang Hospital, Southern Medical University and are diagnosed with primary liver cancer, as well as patients with liver metastases originating from other primary sites.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Voluntarily signed informed consent. Age ≥ 18 years. Patients who require radiotherapy for liver cancer, as determined by the treating physician. Life expectancy \> 3 months. Exclusion Criteria: * Discontinuation of radiotherapy or failure to complete the radiotherapy plan as prescribed. Presence of serious complications or comorbidities that may affect safety.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma liver and intrahepatic bile duct neoplasm Liver Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carcinoma, hepatocellular Liver neoplasms

Contacts and locations

Locations

  • Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People's Republic of China

    Guangzhou, Guangdong, 510515, China

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