New hope to shield kids from deadly transplant side effect
NCT ID NCT01743131
Summary
This study tested if adding a drug called abatacept to the standard medication regimen could better prevent a dangerous immune reaction called Acute Graft versus Host Disease (aGvHD) in patients receiving a bone marrow transplant for blood cancers. The trial involved 186 children and adults who received transplants from unrelated donors. Researchers compared the standard drugs plus a placebo to the standard drugs plus abatacept to see which group had fewer cases of severe aGvHD within the first 100 days after transplant.
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Contacts and locations
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Locations
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Children's Healthcare of Atlanta at Egleston
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Children's and Women's Health Center of BC
Vancouver, British Columbia, V6H 3V4, Canada
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Emory University/Winship Cancer Center
Atlanta, Georgia, 30322, United States
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Michael Grimley
Cincinnati, Ohio, 45229, United States
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Seattle Cancer Care Alliance
Seattle, Washington, 98101, United States
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UCSF Benioff Children's Hospital Oakland
Oakland, California, 94609, United States
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University of Florida
Gainesville, Florida, 32610, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Utah
Salt Lake City, Utah, 84113, United States
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Washington University
St Louis, Missouri, 63141, United States
Conditions
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