New hope to stop deadly transplant complication
NCT ID NCT01743131
Summary
This study tested if adding a drug called abatacept to the standard two-drug regimen could better prevent severe Graft vs Host Disease (GvHD) in patients receiving a stem cell transplant from an unrelated donor. GvHD is a dangerous condition where the donor's immune cells attack the patient's body. The trial involved 186 patients with blood cancers and compared the new three-drug combination against the standard two-drug treatment to see if it was safer and more effective.
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Contacts and locations
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Locations
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Children's Healthcare of Atlanta at Egleston
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Children's and Women's Health Center of BC
Vancouver, British Columbia, V6H 3V4, Canada
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Emory University/Winship Cancer Center
Atlanta, Georgia, 30322, United States
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Michael Grimley
Cincinnati, Ohio, 45229, United States
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Seattle Cancer Care Alliance
Seattle, Washington, 98101, United States
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UCSF Benioff Children's Hospital Oakland
Oakland, California, 94609, United States
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University of Florida
Gainesville, Florida, 32610, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Utah
Salt Lake City, Utah, 84113, United States
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Washington University
St Louis, Missouri, 63141, United States
Conditions
Explore the condition pages connected to this study.