New PET scan may outshine standard in lung cancer detection
NCT ID NCT05617742
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new type of PET scan (68Ga-FAPI) to see if it can find lung cancer and its spread more accurately than the standard FDG-PET scan. 58 adults with known or suspected lung cancer received both scans, and results were compared to tissue samples or follow-up. The goal is to improve diagnosis and staging of lung cancer.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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58 people
The number who actually took part.
- Started
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Dec 2022
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age \> 20 years 2. Informed consent obtained from patients and families 3. Patients with histology confirmed lung cancer or patients with GGO on chest CT planned to have biopsy or surgery 4. Patients scheduled to undergo FDG-PET examination 5. Performance status: 0, 1, 2, 3 Exclusion Criteria: 1. Contraindication to FAPI-PET and FDG-PET such as pregnant, or lactating patients 2. Patients with mainly malignant pleural effusion without other measurable lesions 3. Undergoing irradiation at accrual 4. Active infection or other serious underlying medical conditions not compatible with study entry 5. History of significant neurological or psychiatric disorders including dementia that would prohibit the understanding and giving of informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Nuclear Medicine, Chang Gung Memorial Hospital
Taoyuan, Taiwan
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Other studies related to the condition(s) this trial covers.
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