3D maps could sharpen colon cancer surgery
NCT ID NCT07528937
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a 3D computer model, made from a standard CT scan, helps surgeons better plan operations for locally advanced colon cancer. About 168 adults with stage cT3 or cT4 colon cancer will be randomly assigned to have surgery planned with or without the 3D model. The main goal is to see if the 3D model leads to more complete tumor removals (R0 resection) and fewer complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 3D reconstruction (diagnostic imaging test)
- What this could lead to
- If successful, this could make colon cancer surgery more precise, helping surgeons remove tumors completely and potentially improving patient outcomes.
- What could go wrong
- This is an early-stage study with only 168 participants, and the 3D model may not always be more accurate than standard CT scans. It is not a treatment itself.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 168 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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May 2031
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients of both sexes, aged ≥18 years. 2. Adenocarcinoma of the right, left, sigmoid and recto-sigmoid junction that have cT3 or cT4a/b according to the eighth TNM edition of the American Joint Committee on Cancer (AJCC). Pre-treatment diagnosis by imaging (CT) test. 3. Lymph node extension: cN0, the presence of cN1/2 according to AJCC TNM 8th edition is allowed as long as they can be resected. Pretreatment diagnosis by imaging (CT) test. 4. Patients who access and sign informed consent for the surgical intervention. Exclusion Criteria: 1. Suspected carcinomatosis on preoperative CT or intraoperative finding 2. Suspected distant metastasis on preoperative CT or intraoperative finding 3. Patients with tumors with infiltration considered to be unresectable (pre-surgical or intraoperatively), since the anatomical-pathological analysis will not be available.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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