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3D-Printed tooth repairs put to the test

NCT ID NCT07667946

Knowledge-focused Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how well 3D-printed resin fillings hold up in back teeth with large cavities. Researchers will compare two different ways of shaping the tooth before placing the filling. Fifty adults will be followed for 18 months to see which design leads to fewer cracks or other problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
3D-printed resin composite partial-coverage restoration
What this could lead to
If successful, this could help dentists choose the best cavity design for longer-lasting 3D-printed tooth repairs.
What could go wrong
This is a small, early-stage study with only 50 participants and no comparison to standard materials. Results may not apply to all patients or teeth.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patients aging 20-45 years. 2. Healthy males and females 3. Patients with good oral hygiene 4. Patients presenting with at least one eligible permanent molar requiring a partial-coverage restoration. 5. Patients willing and able to attend scheduled follow-up visits for 18 months. 6. Permanent maxillary or mandibular molars. 7. Vital teeth with a positive response to cold thermal testing. 8. Complex Large or severely compromised cavities resulting from primary or secondary caries (ICDAS 5 or 6) and/or replacement of large defective restorations with at least 2 missing cavity walls requiring overlay restorations 9. Well-formed and fully erupted in normal functional occlusion with natural antagonist and adjacent teeth. 10. Absence of any radiographic, periodontal or periapical changes. Exclusion Criteria: 1. Participants with general/systemic illness. 2. Pregnant or lactating females. 3. Concomitant participation in another research study. 4. Inability or unwillingness to comply with study visits and procedures. 5. Heavy bruxism or other parafunctional habits 6. Known allergic reactions against any components of the used materials 7. Patients receiving orthodontic treatment. 8. Poor oral hygiene or high caries activity. 9. Non vital teeth. 10. Hypersensitive teeth. 11. Teeth with prior endodontic treatment. 12. Teeth with spontaneous pain or signs/symptoms of irreversible pulpitis. 13. Teeth with advanced periodontal disease or mobility. 14. Teeth with a history of direct or indirect pulp capping procedure. 15. Teeth with vertical root fractures or cracked tooth syndrome

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Clinical performance

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.