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UK launches first major study on 22-week preemies to unlock survival secrets

NCT ID NCT07616778

Knowledge-focused Sponsor: Imperial College London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracks babies born at exactly 22 weeks of pregnancy across about 45 UK hospitals. Researchers will collect information from medical records—without names or dates—to see how these extremely premature babies fare and what care they receive. The goal is to fill a huge knowledge gap and give families and doctors better information about what might happen. No treatments are changed; this is purely an observation and learning exercise.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors and families better understand what to expect for babies born at 22 weeks and improve care guidelines.
What could go wrong
This is an observational study, so it won't test any new treatment. It only collects existing data, so it cannot directly improve outcomes for the babies in the study.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

In United Kingdom

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Born at 22+0-22+6 weeks gestational age * Born in a NICU centre with neonatal team in attendance * Or admitted to a NICU within first 72 hours of life if outborn Exclusion Criteria: * Less than or more than 22 weeks gestation at birth * Known congenital anomaly

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Get notified about this study

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Conditions

The condition(s) this trial relates to.

perinatal disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Extreme prematurity - less than 28 weeks Infant, extremely premature Intensive care, neonatal Neonatal and perinatal conditions

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    50 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Imperial College

    RECRUITING

    London, United Kingdom

  • Leeds Neonatal Service

    RECRUITING

    Leeds, United Kingdom

  • Neonatal Surgical Unit, Alder Hey Children's Hospital

    RECRUITING

    Liverpool, United Kingdom

  • Neonatal Surgical Unit, Great Ormond Street Hospital

    RECRUITING

    London, United Kingdom

  • Neonatal Unit, Aberdeen Maternity Hospital

    RECRUITING

    Aberdeen, United Kingdom

  • Neonatal Unit, Arrowe Park Hospital

    RECRUITING

    Upton, United Kingdom

  • Neonatal Unit, Ashford & St Peter's Hospital

    RECRUITING

    Chertsey, United Kingdom

  • Neonatal Unit, Birmingham Heartlands Hospital (University Hospitals Birmingham)

    RECRUITING

    Birmingham, United Kingdom

  • Neonatal Unit, Birmingham Women's and Children's Hospital

    RECRUITING

    Birmingham, United Kingdom

  • Neonatal Unit, Bradford Royal Infirmary

    RECRUITING

    Bradford, United Kingdom

  • Neonatal Unit, Chelsea and Westminster Hospital

    RECRUITING

    London, United Kingdom

  • Neonatal Unit, Derriford Hospital

    RECRUITING

    Plymouth, United Kingdom

  • Neonatal Unit, Homerton University Hospital

    RECRUITING

    London, United Kingdom

  • Neonatal Unit, Hull Royal Infirmary

    RECRUITING

    Hull, United Kingdom

  • Neonatal Unit, James Cook University Hospital

    RECRUITING

    Middlesbrough, Teeside, United Kingdom

  • Neonatal Unit, John Radcliffe Hospital

    RECRUITING

    Oxford, United Kingdom

  • Neonatal Unit, King's College Hospital

    RECRUITING

    London, United Kingdom

  • Neonatal Unit, Lancashire Women & Newborn Centre

    RECRUITING

    Burnley, United Kingdom

  • Neonatal Unit, Leicester Royal Infirmary

    RECRUITING

    Leicester, United Kingdom

  • Neonatal Unit, Liverpool Women's Hospital

    RECRUITING

    Liverpool, United Kingdom

  • Neonatal Unit, Luton & Dunstable Hospital

    RECRUITING

    Luton, United Kingdom

  • Neonatal Unit, Medway Maritime Hospital

    RECRUITING

    Gillingham, United Kingdom

  • Neonatal Unit, New Cross Hospital

    RECRUITING

    Wolverhampton, United Kingdom

  • Neonatal Unit, Ninewells Hospital

    RECRUITING

    Dundee, United Kingdom

  • Neonatal Unit, Norfolk & Norwich University Hospitals

    RECRUITING

    Norwich, United Kingdom

  • Neonatal Unit, Princess Anne Hospital

    RECRUITING

    Southampton, United Kingdom

  • Neonatal Unit, Princess Royal Maternity Hospital

    RECRUITING

    Glasgow, United Kingdom

  • Neonatal Unit, Queen Alexandra Hospital

    RECRUITING

    Portsmouth, United Kingdom

  • Neonatal Unit, Queen Charlotte's and Chelsea Hospital

    RECRUITING

    London, United Kingdom

  • Neonatal Unit, Queen's Medical Centre, University Hospital Nottingham

    RECRUITING

    Nottingham, United Kingdom

  • Neonatal Unit, Rosie Maternity Hospital

    RECRUITING

    Cambridge, United Kingdom

  • Neonatal Unit, Royal Bolton Hospital

    RECRUITING

    Bolton, United Kingdom

  • Neonatal Unit, Royal Jubilee Maternity Hospital

    RECRUITING

    Belfast, United Kingdom

  • Neonatal Unit, Royal London Hospital

    RECRUITING

    London, United Kingdom

  • Neonatal Unit, Royal Oldham Hospital

    RECRUITING

    Oldham, United Kingdom

  • Neonatal Unit, Royal Preston Hospital

    RECRUITING

    Preston, United Kingdom

  • Neonatal Unit, Royal Victoria Infirmary

    RECRUITING

    Newcastle upon Tyne, United Kingdom

  • Neonatal Unit, Simpson Centre for Reproductive Health

    RECRUITING

    Edinburgh, United Kingdom

  • Neonatal Unit, Singleton Hospital

    RECRUITING

    Swansea, Wales, United Kingdom

  • Neonatal Unit, Southmead Hospital

    RECRUITING

    Bristol, United Kingdom

  • Neonatal Unit, St George's Hospital

    RECRUITING

    London, United Kingdom

  • Neonatal Unit, St Mary's Hospital

    RECRUITING

    Manchester, United Kingdom

  • Neonatal Unit, St Michael's Hospital

    RECRUITING

    Bristol, United Kingdom

  • Neonatal Unit, University Hospital Wishaw

    RECRUITING

    Wishaw, United Kingdom

  • Neonatal Unit, University Hospital of North Midlands

    RECRUITING

    Stoke-on-Trent, United Kingdom

  • Neonatal Unit, University Hospital of Wales

    RECRUITING

    Cardiff, Wales, United Kingdom

  • Neonatal Unit, William Harvey Hospital

    RECRUITING

    Ashford, United Kingdom

  • Royal Hospital for Children, Queen Elizabeth University Hospital

    RECRUITING

    Glasgow, United Kingdom

  • The Jessop Wing

    RECRUITING

    Sheffield, United Kingdom

  • University College Hospital

    RECRUITING

    London, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.