New scan could solve mystery of hidden cancer origins
NCT ID NCT07372963
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test a special type of PET/CT scan called 18F-FAPI to see if it can better find where a cancer started when the original source is unknown. About 120 people with cancer of unknown primary will receive the scan, and researchers will measure how accurate it is at detecting the tumor's origin. The goal is to improve diagnosis and help guide treatment decisions.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
120
- Ages
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20 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients with clinical or imaging suspicion of cancer of unknown primary origin. 2. Patients with 18F FAPI PET scans. Exclusion Criteria: 1. Concurrent presence of other active malignant tumors or a history of other malignant tumors within the past 5 years; 2. Severe uncontrollable diseases or active infections; 3. Ineligible participants for project informed consent. 4. Pregnant and lactating women.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310003, China
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Other studies related to the condition(s) this trial covers.
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