10 years later: how does psychotherapy for BPD hold up?
NCT ID NCT07509216
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checks in with people who received mentalization-based treatment (MBT) for borderline personality disorder more than 10 years ago. Researchers want to see how they are functioning now, whether symptoms have changed, and if the type of MBT they received matters. Participants will fill out questionnaires and some will do interviews. No new treatment is given.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- mentalization-based treatment (MBT) - a type of psychotherapy
- What this could lead to
- If successful, this study could reveal how well MBT works in the long run for BPD and which treatment intensity is more effective, helping guide future care.
- What could go wrong
- This is an observational follow-up, not a new treatment trial. Results depend on participants' memory and may not apply to everyone with BPD. There is no new intervention being tested.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 113 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of individuals who previously participated in the randomized controlled trial comparing MBT-DH with MBT-IOP for BPD in the Netherlands. Inclusion criteria were: a BPD diagnosis (SCID-II); age 18 years or older; adequate Dutch language skills; travel time to the MBT clinic of less than one hour. Exclusion criteria: autism spectrum disorder, chronic psychotic disorder or organic brain disorder that significantly interfered with mentalizing; intellectual impairment (IQ \< 80), or antisocial personality disorder with a history of severe physical violence. For this follow-up, all 113 individuals who did not decline future contact will be approached. No new age or diagnostic limits apply. This is a non-probability sample because it consists of the entire available cohort from the original RCT. Participants will initially be invited consecutively to the qualitative substudy; if response permits, purposive sampling will be used to ensure variation.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participation in the original randomized controlled trial of mentalization-based treatment (MBT-DH versus MBT-IOP) * Did not decline to be contacted for future research * Able to provide informed consent at the time of the long-term follow-up assessment (No separate exclusion criteria are specified, as exclusion follows directly from these inclusion criteria.)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Arkin - NPI
Amsterdam, 1093MB, Netherlands
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De Viersprong
Halsteren, 4660AA, Netherlands
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