Xuanwu Hospital, Beijing

This early-stage trial tests whether exosomes from stem cells can help people recover from a recent stroke. 29 participants will receive either the exosome treatment or a placebo, and researchers will check for safety and any signs of improved function. The study is small and exp…

This study tested whether adding sodium sivelestat, a drug that reduces inflammation, to standard mechanical thrombectomy could improve outcomes in 20 stroke patients with large vessel occlusion. The drug aims to prevent 'futile recanalization,' where blood flow is restored but p…

This study tested a new rehabilitation approach for people with spinal cord injury. Ten participants received a spinal cord stimulation implant and used a robotic exoskeleton to help them walk. The goal was to improve leg muscle strength and overall quality of life. The combinati…

This study looked at 250 people with Chiari malformation type I and syringomyelia to compare two surgical approaches: one that opens the covering of the brain and spinal cord, and another that also removes or shrinks the tonsils at the base of the brain. The goal was to see which…

This study looked at a standardized way to diagnose and treat polycystic ovary syndrome (PCOS) in primary care. Researchers worked with 227 women aged 18-50 to see if a structured care plan, including lifestyle changes and prebiotic supplements, could improve insulin resistance a…

This study tested whether a clot-busting drug called rhTNK-tPA can help people having a stroke when given 4.5 to 24 hours after symptoms begin. It included 570 adults with a stroke that did not involve a large blocked artery. The goal was to see if the drug leads to better recove…

Researchers are testing a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) in adults with chronic neuropathic pain. The trial compares three approaches: stimulating two brain targets alternately, stimulating one target, or a sham (pla…

This study tested whether daily 20-minute warm baths could safely reduce seizures in 8 children (ages 6 months to 6 years) with CDKL5 deficiency, a rare genetic disorder causing hard-to-control seizures. The treatment was added to their usual medications for 12 weeks. The goal wa…

This study tested whether a pre-surgery health optimization program (prehabilitation) combined with enhanced recovery after surgery (ERAS) can reduce complications in elderly patients undergoing spinal fusion. 164 participants were randomly assigned to receive either the PREERAS …

Researchers are observing how two osmotic therapies, 20% mannitol and 10% hypertonic saline, affect outcomes in adults with severe subarachnoid hemorrhage, a type of bleeding around the brain. The study follows patients at multiple hospitals who receive standard care chosen by th…

This study looked at 1180 adults with dural arteriovenous fistulas (abnormal connections between arteries and veins in the brain lining). Researchers tracked patients' recovery and complications after treatment, as well as how often the condition came back. The goal was to gather…

This study looked at how fever changes seizure patterns in people with CDKL5 deficiency disorder, a rare genetic condition that causes hard-to-control seizures. Researchers surveyed parents of 131 affected individuals to collect information on fever history and seizure frequency.…

This study looked at how blood pressure and heart rate change in the hour after an epileptic seizure. Researchers measured these vital signs at several time points in 1,100 people with epilepsy. The goal was to better understand the body's response right after a seizure, which ma…

This completed observational study followed 3,849 people with asymptomatic intracranial atherosclerosis (narrowing of brain arteries) to better understand how the disease progresses and to improve stroke prediction. Participants underwent routine imaging and cognitive tests over …