University Of Southampton

Researchers are testing a vaccine called BNT113 in people whose cancers are driven by HPV16, a common virus linked to head and neck, cervical, and anogenital tumors. The trial enrolls two groups: one with head and neck cancer that has been treated and shows no signs of disease, a…

This phase 2 trial tested a two-step treatment for advanced esophageal cancer that has a specific genetic marker (MGMT deficiency) and has stopped responding to standard chemotherapy. First, patients took a daily oral chemotherapy drug (temozolomide) for three months. Then, they …

This study compared an automatic ABPI device (MESI MD) with the standard manual device (Huntleigh Dopplex) in 46 patients with lower limb ulcers. The goal was to see if the automatic device gives similar scores and ulcer classifications, potentially reducing waiting times and dis…

This study tested whether a team-based plan to reduce certain medications (anticholinergics) is practical and acceptable for older hospital patients. 21 people aged 65+ with high anticholinergic burden took part. Researchers measured medication changes, daily function, and safety…

This study looked at how often older adults feel anxious or depressed after breaking a bone from a fall and having surgery. Researchers used a simple questionnaire to check symptoms in 40 patients aged 65 and older, both those who had surgery and those who did not. The goal was t…

This study tested a new plate imaging system to measure how much food stroke patients eat in the hospital. Fifty patients on a stroke rehabilitation ward had their meals photographed to estimate calorie and nutrient intake. The goal was to see if this simple, non-invasive method …

This study followed 461 children whose mothers took a special nutritional drink before and during pregnancy. Researchers want to understand how parents' diet, lifestyle, and metabolism influence child growth, thinking skills, and overall well-being. The goal is to identify factor…