Universitätsklinikum Hamburg-eppendorf

This trial compares two types of replacement heart valves used in a procedure called TAVI for people with severe aortic valve stenosis and a small aortic annulus. The two valves are the Meril Octapro+ and the Abbott Navitor. Researchers want to see which design provides better sa…

This trial tests whether a less intensive antiplatelet therapy is safer and as effective as standard dual therapy for people with spontaneous coronary artery dissection (SCAD), a rare cause of heart attack in women aged 30–55. Unlike typical heart attacks, SCAD involves a tear in…

This study tests a new five-drug combination for people newly diagnosed with a high-risk form of multiple myeloma. The drugs include etentamig, isatuximab, bortezomib, lenalidomide, and dexamethasone. The trial will enroll 220 participants and first check safety, then see if the …

This study evaluates a multicomponent care program designed to prevent postoperative delirium in adults aged 65 and older undergoing surgery. The program includes preoperative screening for risk factors like frailty and cognitive impairment, patient and family education, and indi…

This study investigates persistent idiopathic facial pain (PIFP), a chronic condition where people feel facial pain without any obvious nerve damage or dental cause. Researchers will compare 60 participants, including people with PIFP and healthy volunteers, using sensory tests a…

This study looks at whether a routine blood test measuring D-dimer levels can predict if the immunotherapy drug cemiplimab will control advanced cutaneous squamous cell carcinoma. Researchers will follow 116 patients starting cemiplimab in regular care, comparing disease control …

This study looks at how positive expectations—like thinking you received a helpful treatment—can change how your brain processes emotions. Healthy adults will receive a saline nasal spray labeled as either oxytocin or saline on different days. Researchers will measure mood, brain…

This study gathers 30 skin experts to agree on the safest ways to perform radiofrequency microneedling, a popular cosmetic treatment for tightening skin. They will create guidelines on who should get the treatment, how to do it safely, and how to avoid complications. No patients …