Tianjin Medical University Cancer Institute And Hospital

This study tests a combination of three drugs—fruquintinib (targeted therapy), an immune checkpoint inhibitor (immunotherapy), and TAS-102 (oral chemotherapy)—in people with advanced colorectal cancer that has stopped responding to standard treatments. The goal is to see if this …

This phase 2 trial is testing a combination of three drugs—oral etoposide (chemotherapy), anlotinib (targeted therapy), and envafolimab (immunotherapy)—as a first treatment for elderly patients with extensive small cell lung cancer. The study will enroll 30 participants to see if…

This early-stage trial is testing a new treatment called GK01 cell injection, given together with a PD-1 monoclonal antibody (a type of immunotherapy), for people with advanced solid tumors that have spread or come back. The study includes about 15 adults aged 18 to 70 with cance…

This phase 2 trial is testing a combination of two immunotherapy drugs (sintilimab and ipilimumab) plus chemotherapy (albumin-bound paclitaxel and gemcitabine) as a first treatment for people with advanced bile duct or gallbladder cancer that cannot be removed by surgery. The stu…

This early-phase study tests whether combining two drugs, cadonilimab and regorafenib, can help people with advanced liver cancer whose disease has worsened after at least one prior treatment. About 30 adults will receive the combination to see if tumors shrink and how safe the t…

This study tests a combination of chemotherapy, immunotherapy, and a targeted drug given directly into the liver's blood supply to shrink tumors in people with liver cancer that may be removable with surgery. The goal is to see if this approach can make surgery more effective and…

This study tests whether adding an immunotherapy drug (treprizumab) to standard chemotherapy before surgery can improve outcomes for people with advanced head and neck cancer. About 122 participants will be randomly assigned to receive either the drug combo or chemo alone for thr…

This study tests whether adding the drug surufatinib to standard chemotherapy can help shrink pancreatic tumors enough to allow successful surgery. It involves 29 adults with locally advanced or borderline resectable pancreatic cancer. The main goal is to see how many tumors can …

This study tests a personalized, high-dose radiation therapy (SBRT) for people with early-stage peripheral non-small cell lung cancer who cannot have surgery or choose not to. The goal is to see if this tailored approach controls the tumor and helps patients live longer with fewe…

This trial tests whether an AI-based management platform, called 'Zhiliao Doctor,' can reduce anxiety and depression in 300 breast cancer patients taking CDK4/6 inhibitors at home. Participants are randomly assigned to standard care, the AI platform, or personalized follow-up cal…

This study reviews medical records from 300 cancer patients to see if the makeup of a tumor's surroundings (the tumor microenvironment) is linked to how well antibody-based therapies work. Researchers will analyze tissue samples and blood tests from patients with seven cancer typ…

This study looks at whether using a laparoscopic camera to check for cancer spread in the abdomen helps doctors choose better treatments for people with stage III stomach cancer. About 968 participants will be randomly assigned to either get this staging procedure or not. The mai…

This study looks back at medical records from 400 older adults (age 60+) with Hodgkin lymphoma in China. Researchers are collecting information on patient characteristics, treatments, and survival to build a model that can predict how the disease will progress. The goal is to hel…

This study looked back at the medical records of 800 adults with liver cancer that could not be removed by surgery. All patients were treated with lenvatinib, a targeted therapy, at six hospitals. The goal was to see how long patients lived and how well the treatment worked in ev…