The Third Xiangya Hospital Of Central South University

This Phase 2 trial tests whether adding two drugs (benmelstobart and anlotinib) to standard chemotherapy before chemoradiation helps people with stage III lung cancer that cannot be removed by surgery. 152 participants will be randomly assigned to receive either the new induction…

This early-phase trial will test a new tumor vaccine (SapDM275) combined with standard chemotherapy in 13 people with metastatic pancreatic cancer who haven't had prior treatment. The vaccine aims to train the immune system to attack stress proteins on cancer cells. The main goal…

This study looks at 120 adults with type 2 diabetes to see if using a continuous glucose monitor (CGM) helps control blood sugar better than traditional finger-stick testing, when both groups take the drug dapagliflozin. Participants will manage most of the study from home using …

This study tests whether choosing blood pressure drugs based on a person's specific heart function (called hemodynamic phenotyping) leads to better blood pressure control than the usual guideline-based method. About 240 adults with mild to moderate hypertension who have never tak…

This study tests an oral traditional Chinese medicine made from the fungus C. cicadae in people with ALS who have high levels of certain fats (sphingolipids) in their blood. About 84 participants will receive either the medicine or a placebo for 6 months, with follow-up for 9 mon…