The Lymphoma Academic Research Organisation

This study tests whether adding venetoclax to a standard treatment (ibrutinib plus a CD20 antibody) works better for people newly diagnosed with mantle cell lymphoma, a rare blood cancer. About 210 adults aged 18 to 79 will receive either the standard combo or the standard combo …

This study tests a CAR T-cell therapy called axi-cel as a second treatment for people with aggressive B-cell lymphoma that has come back or not responded to initial therapy, and who cannot have a stem cell transplant. About 62 participants will receive a one-time infusion of thei…

This study tests an experimental drug called valemetostat tosylate in 141 people with B-cell lymphoma that has returned or stopped responding to standard treatments. The drug is taken alone and aims to shrink tumors. The study includes six different lymphoma types, including aggr…