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New combo therapy aims to stop aggressive lymphoma relapse

NCT ID NCT06271057

First seen Jun 04, 2026 · Last updated Jun 12, 2026 · Updated 1 time

Summary

This study tests whether adding a drug called golcadomide after standard CAR T-cell therapy can prevent aggressive large B-cell lymphoma from returning in patients at high risk of relapse. About 65 adults will receive golcadomide for 24 weeks starting 5 days after their CAR T-cell infusion. The main goal is to see if more patients achieve a complete response (no cancer detected) at 3 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Henri Becquerel

    RECRUITING

    Rouen, 76038, France

    Contact Email: •••••@•••••

    Contact

  • Chru de Lille

    RECRUITING

    Lille, 59037, France

    Contact Email: •••••@•••••

    Contact

  • Chu Brabois

    RECRUITING

    Vandœuvre-lès-Nancy, 54511, France

    Contact Email: •••••@•••••

    Contact

  • Chu Dijon Bourgogne

    RECRUITING

    Dijon, 21000, France

    Contact Email: •••••@•••••

    Contact

  • Chu Pontchaillou

    RECRUITING

    Rennes, 35033, France

    Contact Email: •••••@•••••

    Contact

  • Chu de Bordeaux

    RECRUITING

    Pessac, 33604, France

    Contact Email: •••••@•••••

    Contact

  • Chu de Grenoble

    RECRUITING

    La Tronche, 38700, France

    Contact Email: •••••@•••••

    Contact

  • Chu de Montpellier

    RECRUITING

    Montpellier, 34090, France

    Contact Email: •••••@•••••

    Contact

  • Chu de Nantes

    RECRUITING

    Nantes, 44093, France

    Contact Email: •••••@•••••

    Contact

  • Hopital Henri Mondor

    RECRUITING

    Créteil, 94010, France

    Contact Email: •••••@•••••

    Contact

  • Hopital Saint-Louis

    RECRUITING

    Paris, 75475, France

    Contact Email: •••••@•••••

    Contact

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, 13273, France

    Contact Email: •••••@•••••

    Contact

  • Iuct Oncopole

    RECRUITING

    Toulouse, 31059, France

    Contact Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma high grade B-cell lymphoma marginal zone lymphoma primary mediastinal large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.