Texas Tech University

This study compares two weight-loss strategies: GLP-1 medications (like semaglutide or tirzepatide) versus a structured diet and exercise program. Adults with a BMI of 27.5 or higher are followed for three months to see which approach better improves heart and metabolic markers, …

This study investigates whether taking resveratrol—a compound found in red wine—can improve the muscle, blood vessel, and brain benefits of strength training in adults aged 60 and older. Participants will take resveratrol or a placebo while following a supervised strength trainin…

This study tests whether applying heat pads to the legs for 90 minutes a day can improve blood sugar control, muscle health, and physical function in older adults with prediabetes. Researchers will compare the effects to high-intensity interval training. The goal is to find a sim…

This study tests whether a 4-week emotion regulation and self-monitoring program can help overweight and obese teens ages 11-14. Participants attend weekly telehealth groups and track their mood and health behaviors. Researchers will measure changes in brain activity, blood marke…

This study tests a type of talk therapy called acceptance and commitment therapy (ACT) for people with mild dementia and their care partners. The goal is to see if it helps reduce depression, anxiety, and grief. About 100 pairs will take part, either in person or online.

This study tests whether adding two check-in calls per week to standard cognitive behavioral therapy (CBT) improves quality of life for adults caring for a family member with dementia in rural Texas. Sixty caregivers will receive either individual CBT for 12-16 weeks or CBT plus …

This study tests whether online (telehealth) programs can reduce pre-death grief, burden, and stress in family caregivers of people with dementia. About 60 adult caregivers who speak English and have a mental health condition like anxiety or depression will take part. The goal is…

This study tests whether group or individual therapy can reduce pre-death grief, burden, and stress in people caring for a loved one with dementia. About 60 informal caregivers (family or close friends) will participate. The goal is to improve their emotional well-being during a …

This observational study will follow 100 adults starting anti-obesity medications like semaglutide or tirzepatide. Researchers will track changes in body fat, lean muscle, bone density, handgrip strength, and nutrition over time. The goal is to understand the real-world effects o…

This study looks at why young adults born very preterm often don't get fitter from aerobic exercise. Researchers will compare mitochondrial DNA and fitness changes between 60 preterm-born and full-term adults after a 4-5 day per week exercise program. The goal is to find mitochon…

This study looks at how mild dehydration (losing 2-3% of body weight through water) and then rehydrating affects inflammation, blood sugar, sleep, and strength in adults aged 45-65. Fifteen healthy participants will follow a 12-day hydration schedule, with five lab visits to meas…