Tan Tock Seng Hospital

This study tests whether stable patients with a common blood infection (gram-negative bacteraemia) can safely switch from IV antibiotics to oral pills within 72 hours. Researchers will compare early oral therapy to continued IV treatment in 720 adults. The main goal is to see if …

This study tests a device called CRYSTALSIGHT that tracks eye movements to detect if wet age-related macular degeneration (AMD) has come back. About 60 adults aged 55 to 99 who are being treated for wet AMD will use the device at home. The goal is to see if it works as well as th…

This study tests whether a gentle electrical current applied to the brain (called tDCS) can improve arm movement in people who recently had a stroke. Fifty patients with severe arm weakness will receive either real or sham stimulation during rehab. The goal is to see if this pain…

This study tests a robotic glove that reads brain signals to help people who have had a stroke move their affected hand and arm. The goal is to improve function and dexterity. The trial will include 60 adults who had a stroke at least 16 weeks ago and have limited hand movement.

This study tests whether watching a short educational video before a planned heart procedure (called PCI) can help lower anxiety. About 144 adults will take part, with some watching the video and others receiving usual care. Anxiety levels are measured before and after using a st…

This study involves giving a weakened dengue virus to 5 healthy adults aged 21-45 in Singapore to safely study how the body fights the infection. The goal is to create a reliable model for testing future dengue vaccines and treatments. Participants will be closely monitored for s…

This study aims to establish what normal binocular single vision (using both eyes together) looks like for healthy adults in Singapore, aged 21 to 59. Current standards are based on a small 1974 study of Caucasians, which may not apply to Asian populations. Researchers will measu…