Taiho Oncology, Inc.

This study looks at how the body handles the cancer drug ASTX727 in people with severe kidney impairment compared to those with normal kidneys. It includes adults with certain blood cancers or solid tumors. The goal is to understand safety and drug levels, not to cure the disease…

This study tests two doses (20 mg and 16 mg) of the drug futibatinib in 120 people with advanced bile duct cancer that has a specific FGFR2 gene change. Participants must have already tried standard chemotherapy. The goal is to see if the drug shrinks tumors and how safe it is. T…

This study looks at how the cancer drug ASTX727 (decitabine and cedazuridine) is processed by the body in people with moderate or severe liver problems. About 27 adults with certain blood cancers or solid tumors will take the drug for up to 8 weeks. The goal is to find safe dosin…

This study tests an oral drug (ASTX030) that combines two medicines to treat certain blood cancers like MDS and AML. The goal is to see if taking a pill works as well as getting a shot, and if it can be safely combined with another drug (venetoclax) for AML. About 316 adults will…

This study tests an experimental drug called zipalertinib in people with advanced non-small cell lung cancer that has certain changes in the EGFR gene. About 220 adults will take the drug to see if it shrinks tumors and how safe it is. The goal is to control the disease, not cure…