St. Jude Children's Research Hospital

This study is testing whether a new type of immune cell therapy can help prevent cancer from coming back in children with high-risk bone cancer (osteosarcoma). After children finish their standard chemotherapy, doctors will give them specially engineered immune cells designed to …

This study is testing whether a weekly weight-loss medication (Tirzepatide) combined with a remote, supervised exercise program can help adult survivors of childhood leukemia lose weight and improve their heart and metabolic health. The 28-week program aims to see if participants…

This study is testing whether a 12-week program of high-intensity interval training (HIIT) is a practical and helpful exercise option for young people who have recently finished treatment for Hodgkin lymphoma. The research will see if survivors can stick with the program and if i…

This study is testing whether wearing special light therapy glasses can help reduce depression, fatigue, and sleep problems in children and teenagers who are receiving a stem cell transplant. About 98 participants, aged 8 to 18, will wear the glasses for 30 minutes a day for four…

This study aims to better understand the side effects of asparaginase, a drug commonly used to treat childhood leukemia. Researchers will collect data and perform liver scans on 200 children and young adults receiving standard leukemia treatment. The goal is to measure how often …

This study is testing whether adult survivors of childhood cancer will use a remote monitoring program to track their heart and metabolic health. Participants will wear devices, complete surveys, and do lab tests from home over 12 weeks. The goal is to see if this remote approach…

This study aims to learn if a non-invasive light therapy, aimed at the forehead, can improve thinking skills and oxygen use in the brains of children with sickle cell disease. Researchers will enroll 60 children, aged 8-17, who will be randomly assigned to receive either the real…

This study aims to understand the long-term effects of gene therapy on the liver in adults with hemophilia. Researchers will analyze small liver tissue samples from up to 8 people who received gene therapy at least 6 months ago. The goal is to see how the liver cells have respond…