Shionogi

This study tests an experimental drug called S-531011, alone or with other cancer treatments, in people with advanced solid tumors that have not responded to standard therapies. The goal is to find the safest dose and see if it can shrink tumors or slow cancer growth. About 282 p…

This study tests whether adding the experimental drug S-606001 to standard enzyme replacement therapy can help adults with late-onset Pompe disease breathe better and walk farther. About 45 participants will receive either the drug or a placebo, and researchers will monitor safet…

This study tests an experimental antiviral drug, S-337395, in adults with RSV who are not hospitalized but have health conditions that put them at high risk for severe illness. Participants receive either the drug or a placebo within 72 hours of symptoms starting. The main goal i…

This study tests a drug called naldemedine in children (up to age 18) who are taking or about to take opioids for pain. The drug aims to relieve constipation caused by opioids. Researchers will check how the drug moves through the body and if it is safe. About 24 children will ta…

This study looks at how the body handles a new drug called S-892216 in people with mild, moderate, or severe kidney problems, including those on dialysis, compared to people with healthy kidneys. About 40 adults will take a single dose of the drug, and researchers will measure dr…