Rutgers, The State University Of New Jersey

This phase 2 study tests the drug pembrolizumab in 21 people with advanced solid tumors that have specific gene changes (BRCA1, BRCA2, POLE, or POLD1). The goal is to see if the drug can shrink or stop the cancer from growing. This is not a cure, but a way to control the disease.

This study tests a one-month treatment for latent tuberculosis (TB) in people waiting for a kidney transplant. The goal is to see if the treatment is safe and easy to complete. 25 adults with end-stage kidney disease and latent TB will take the medication and be monitored for sid…

This study was designed to test whether combining three drugs—rituximab, venetoclax, and bortezomib—could shrink or stop the growth of an aggressive type of lymphoma (DLBCL) that had come back or not responded to prior treatment. The trial was withdrawn before enrolling any parti…

This study tests whether giving a powerful mix of chemotherapy drugs (FOLFOXIRI) along with standard chemoradiation before surgery can make rectal cancer disappear completely. About 38 adults with rectal cancer will receive the experimental treatment, then have scans to check tum…

This study tests whether giving a short course of radiation to part of the breast before surgery is safe and practical for women with early-stage breast cancer. About 98 women over age 50 with small, hormone-sensitive tumors will receive radiation before their operation. Research…

This study tests whether a new personalized feedback program can help 660 young adults (ages 18-25) reduce risky alcohol and drug use. Participants answer questions about their habits and receive tailored feedback. The goal is to see if this approach lowers substance use and incr…

This study compares over-the-counter pain relievers to opioid painkillers for managing pain after wisdom tooth removal. About 1,800 people will rate their pain and satisfaction over a week. The goal is to see if non-opioid options work just as well, which could help reduce opioid…

This study tests a program called Bright IDEAS that teaches problem-solving skills to young adults (ages 18-39) recently diagnosed with cancer. The goal is to see if it reduces symptoms of depression and anxiety and improves quality of life compared to standard support. 344 parti…

This study tests a program called Journey Ahead for 30 women with gynecologic cancers like ovarian or uterine cancer. The program focuses on improving coping skills and communication to reduce depressive symptoms and distress. Participants will complete surveys over time to measu…

This study tests whether a nerve block given before heart surgery can reduce pain and the need for strong painkillers like opioids afterward. About 150 adults having certain heart surgeries will receive either a long-lasting or standard numbing medicine. The goal is to see which …

This study looks at whether a daily grape powder drink can reduce anxiety, depression, and stress in healthy college students aged 18-30. For 4 weeks, 50 participants will take either grape powder or a placebo and provide surveys and stool samples. The goal is to see if the powde…

This study looks at whether involving a radiation specialist early in care can improve quality of life for adults with metastatic cancer that cannot be cured. About 156 participants will either get standard cancer care alone or standard care plus early radiation oncology input. T…

This study looks at whether a private Facebook group can help young adults (ages 18-39) diagnosed with early-stage melanoma and their close family members do more skin self-exams and get full-body skin checks. About 1,160 participants from New Jersey, California, and Texas will j…

This small pilot study aims to see if wearable devices like smartwatches can help measure changes in autism symptoms during treatment with sulforaphane, a compound found in vegetables. Ten males aged 13-30 with autism who previously took part in a sulforaphane study will wear non…

This study tests whether a family wellness program helps Latino children who speak Spanish at home get ready for kindergarten. About 400 families will either join an 8-week summer program with text messages and booster sessions, or receive usual care plus school supplies. Researc…

This study aimed to create a mobile app to help people with opioid prescriptions use, store, and dispose of their medication safely. Researchers planned to work with patients and doctors to design the app and test it in a small trial. However, the study was withdrawn before any p…