Nuvation Bio Inc.

This study tests whether the drug taletrectinib can prevent lung cancer from returning in people with a specific genetic marker (ROS1) after their tumor has been surgically removed. About 180 adults with stage IB to IIIA non-small cell lung cancer will receive either taletrectini…

This study tests a drug called safusidenib in adults with a specific type of brain tumor (glioma) that has an IDH1 mutation. The goal is to see if the drug can shrink tumors or slow their growth. The trial has three parts, involving people with different stages of the disease, an…

This study compares a new drug, taletrectinib, to the standard drug crizotinib in people with a specific type of advanced lung cancer (ROS1-positive non-small cell lung cancer) who have not had targeted therapy before. About 194 participants will be randomly assigned to take one …