New hope for rare lung cancer: taletrectinib takes on crizotinib in phase 3 showdown
NCT ID NCT06564324
First seen Nov 21, 2025 · Last updated May 18, 2026 · Updated 25 times
Summary
This study compares a new drug, taletrectinib, to the standard drug crizotinib in people with a specific type of advanced lung cancer (ROS1-positive non-small cell lung cancer) who have not had targeted therapy before. About 194 participants will be randomly assigned to take one of the two pills daily. The goal is to see if taletrectinib is better at delaying cancer growth or death.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Beijing Cancer Hospital
RECRUITINGBeijing, Beijing Municipality, China
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Cancer Hospital Chinese Academy of Medical Sciences
NOT_YET_RECRUITINGBeijing, Beijing Municipality, China
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Cancer Hospital of Shandong First Medical University
RECRUITINGJinan, Shangdong, China
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Chongqing University Cancer Hospital
RECRUITINGChongqing, Chongqing Municipality, China
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Guangxi Medical University Cancer Hospital
RECRUITINGNanning, Guangxi, China
Contact
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Henan Cancer Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, China
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Hunan Cancer Hospital
RECRUITINGChangsha, Hunan, China
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Jiangsu Province Hospital
RECRUITINGNanjing, Jiangsu, China
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Linyi Cancer Hospital
RECRUITINGLinyi, Shandong, China
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Shanghai East Hospital
RECRUITINGShanghai, Shanghai Municipality, China
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Shanghai Pulmonary Hospital
RECRUITINGShanghai, Shanghai Municipality, China
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Shanxi Cancer Hospital
RECRUITINGTaiyuan, Shanxi, China
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Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, China
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The First Affiliated Hospital of Anhui Medical University
RECRUITINGHefei, Anhui, China
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The First Affiliated Hospital of Guangdong Pharmaceutical University
RECRUITINGGuangzhou, Guangdong, China
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The First Affiliated Hospital of Guangzhou Medical University
RECRUITINGGuangzhou, Guangdong, China
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The First Affiliated Hospital of Nanchang University
RECRUITINGNanchang, Jiangxi, China
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The First Affiliated Hospital of Soochow University
RECRUITINGSuzhou, Jiangsu, China
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The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITINGXi’an, Shanxi, China
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The First Affiliated Hospital of Xiamen University
RECRUITINGXiamen, Fujian, China
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The First Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, Henan, China
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The First Hospital of China Medical University
RECRUITINGShenyang, Liaoning, China
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The Fourth Hospital of Hebei Medical University
RECRUITINGShijiazhuang, Hebei, China
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Tianjin Cancer Hospital
RECRUITINGTianjin, Tianjin Municipality, China
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Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, China
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West China Hospital of Sichuan University
RECRUITINGChengdu, Sichuan, China
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Yunnan Cancer Hospital
NOT_YET_RECRUITINGKunming, Yunnan, China
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Zhejiang Cancer Hospital
RECRUITINGHangzhou, Zhejiang, China
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Zhongshan Hospital, Fudan University
RECRUITINGShanghai, Shanghai Municipality, China
Contact
Conditions
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