Modernatx, Inc.

This early-stage study is testing an experimental mRNA vaccine called mRNA-1189 to see if it is safe and can trigger an immune response against Epstein-Barr virus (EBV). The trial involves 120 healthy adults aged 18 to 30. Researchers will compare two ways of giving the vaccine: …

This study tests an mRNA vaccine (mRNA-1647) to prevent cytomegalovirus (CMV) infection in people who have had a stem cell transplant. About 224 participants will receive either the vaccine or a placebo. The goal is to see if the vaccine can safely prevent serious CMV infections …

This study is testing an updated COVID-19 vaccine (mRNA-1283) to see how well it protects against current virus variants and if it is safe. About 832 adults, especially those 65 and older or with risk factors, will receive the vaccine. Researchers will measure immune response and…

This study tests updated mRNA COVID-19 vaccines designed to target new virus variants. About 1,144 people will receive the vaccine to see how well it boosts immunity and if it is safe. The goal is to keep protection strong as the virus changes.

This study is for people with propionic acidemia who have already taken part in a previous study of the experimental drug mRNA-3927. The main goal is to see if the drug is safe over a longer period of time. Researchers will also track how often participants have serious metabolic…

This study looks at the long-term safety and effects of an experimental medicine called mRNA-3705 for people with methylmalonic acidemia (MMA), a rare genetic disorder that prevents the body from breaking down certain proteins and fats. Participants have already taken part in ear…

This study tests an experimental mRNA medicine called mRNA-3927 for people with propionic acidemia, a rare genetic condition that causes dangerous metabolic crises. The trial enrolls about 77 participants aged 1 year and older to evaluate safety and whether the drug can reduce th…

This study tests an experimental mRNA medicine called mRNA-2808 in people whose multiple myeloma has returned or stopped responding to standard treatments. The main goals are to check safety and see if the treatment can shrink tumors or slow the cancer. About 166 adults will take…

This study tests a new medicine called mRNA-1195 in 180 adults aged 18 to 55 who have multiple sclerosis (MS). The goal is to see if it is safe and how the body reacts to it. Participants will receive either the study drug or a placebo as a shot into the muscle. The study will al…

This study reviews medical records of 60 people with propionic acidemia, a rare genetic disorder. Researchers will track metabolic crises, hospital visits, and other health events. The goal is to better understand the disease and its impact, which may help improve future treatmen…