Michael J. Fox Foundation For Parkinson's Research

Researchers are testing whether a high-resolution PET camera can track brain changes in Parkinson's disease better than a standard PET camera. About 45 people with Parkinson's and 5 healthy volunteers receive an injection of a radioactive tracer called [18F]AV-133, then undergo b…

Researchers are comparing two PET cameras, a high-resolution one called NeuroEXPLORER and a standard Siemens Biograph, to see which better detects brain changes in people with prodromal Parkinson's disease. About 25 participants from an existing Parkinson's study will receive sca…

This observational study collects health information from up to 500,000 adults with and without Parkinson's disease. Researchers aim to identify risk factors and early signs that predict who may develop the disease and how it progresses. Participants report their symptoms and med…

This study is testing whether a special PET imaging tracer, [18F]PI-2620, can detect tau protein buildup in the brains of people with Parkinson's disease, including those with a genetic form linked to the LRRK2 gene. About 60 participants will undergo high-resolution brain scans …

This observational study, led by the Michael J. Fox Foundation, aims to understand how Parkinson's disease progresses over time. It will follow 4,500 people, including those with Parkinson's, those at risk, and healthy volunteers, collecting clinical, imaging, and genetic data. T…

BLAAC PD is a research study that aims to understand what Parkinson's disease looks like for Black and African American communities. Researchers will collect genetic and health information from 2,000 participants across the U.S. to explore risk factors and genetic causes of Parki…

This study is testing whether a special PET scan using a tracer called [18F] AV-133 can track changes in the brain of people with early, or 'prodromal,' Parkinson's disease. About 100 participants will be scanned at the start, after 12 months, and after 24 months. The goal is to …